CEA is a glycoprotein involved in cell adhesion. It is normally produced during foetal development, but the production of CEA stops before birth. It is of interest in oncology as many carcinomas secrete CEA which can be measured in patient serum. CEA.6G11 and CEA.6H9 are high affinity sheep monoclonal antibodies that bind to different epitopes on CEA

CEA.6G11

Colon cancer biomarker. Binds with high-affinity to human CEA.

CEA.6H9

Binds with high-affinity to a different epitope on human CEA than CEA.6G11

Reference: Hybridoma 1999 Apr;18(2):183-91. Novel super-high affinity sheep monoclonal antibodies

against CEA bind colon and lung adenocarcinoma.

Note: for in vitro diagnostic use only